![]() ![]() Existen diferentes métodos de medida, aunque en este artículo nos referiremos sobre todo a la técnica de la respiración única, la más utilizada y mejor estandarizada. Actualmente hay nuevos métodos para medir la capacidad de difusión utilizando óxido nítrico (NO). La capacidad de difusión es la técnica que mide la capacidad del aparato respiratorio para realizar el intercambio gaseoso y así diagnosticar la disfunción de la unidad alvéolo-capilar.Įl parámetro más importante a evaluar es la capacidad de difusión del CO (DLCO). Other causes of decreased or increased DLCO are also highlighted. There is a decrease in DLCO in patients with alveolar volume reduction or diffusion defects, either by altered alveolar-capillary membrane (interstitial diseases) or decreased volume of blood in the pulmonary capillaries (pulmonary embolism or primary pulmonary hypertension). An increase in the transfer of CO occurs in diseases in which there is an increased volume of blood in the pulmonary capillaries, such as in polycythemia and pulmonary haemorrhage. ![]() Clinical applications are also discussed. The practical aspects of the technique are analysed, by specifying the recommendations to carry out a suitable procedure, the calibration routine, calculations and adjustments. Its complexity, its reference equations, differences in equipment, inter-patient variability and conditions in which the DLCO is performed, lead to a wide inter-laboratory variability, although its standardisation makes this a more reliable and reproductive method. There are other methods for measuring diffusion, although in this article the single breath technique is mainly referred to, as it is the most widely used and best standardised. New methods are currently being used to measure the diffusion using nitric oxide (NO). The most important parameter to assess is the CO diffusion capacity (DLCO). The diffusion capacity is the technique that measures the ability of the respiratory system for gas exchange, thus allowing a diagnosis of the malfunction of the alveolar-capillary unit. ![]()
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